Scientifically Designed to Support a Healthy Mood and Methylation. Features clinically effective levels of SAMe and body-ready folate and vitamin B12.Blisphora™ is a revolutionary formula featuring clinically effective levels of SAMe (s-adenosyl-L-methionine), a compound native to the body that is a critical component of many biochemical reactions and plays an important role in supporting positive emotions. This powerful formula combines significant levels of body-ready folate (the next generation of folate with improved bioavailability) and vitamin B12 (as easy-to-absorb methylcobalamin) to support SAMe metabolism, methylation, and healthy neurotransmitter synthesis for a balanced mood.* Foil-wrapped, enteric-coated tablets ensure product stability.